Dr. Aymeric Leray (1979), chercheur CNRS, a obtenu sa thèse en Physique en 2005 à l’université de Rennes (France). Après un premier post-doc avec Jerome Mertz à Boston University (USA) et un second avec Laurent Héliot à l’Institut de Recherche Interdisciplinaire (IRI) à Lille, il est recruté en 2010 en tant que chercheur CNRS dans le groupe Biophotonique à l’IRI à Lille. Depuis 2014, il travaille à l'ICB. Ses travaux de recherche gravitent principalement autour de la microscopie optique non linéaire appliquée à la Biologie et de la détection de molécules uniques pour les biocapteurs.
- – ANR SpecTra (Etude spectroscopique de nanoparticules piégées optiquement), 2016-2020
- – Equipex ImaginEx BioMed (Imagerie innovante d’excellence dans le domaine biomédical: plateforme de criblage à haut-débit et à très haut-contenu), 2011-2021
A readily usable two-photon fluorescence lifetime microendoscope
Charles-Henri Hage, Pierre Leclerc, Marc Fabert, Sylvia M. Bardet, Julien Brevier, Guillaume Ducourthial, Tigran Mansuryan, Aymeric Leray, Alexandre Kudlinski, Frederic Louradour,Journal : J. Biophotonics - n° 12 - 2019 -
Conformational Changes and Charge Transfer in Biomolecules Resolved Using Dynamic Enhanced Raman Correlation Spectroscopy
Aymeric Leray, Jean-Emmanuel Clement, Alexandre Bouhelier, Eric Finot,Journal : J. Phys. Chem. B - n° 123 - 2019 - 1931-1938
Spectral pointillism of enhanced Raman scattering for accessing structural and conformational information on single protein
Jean-Emmanuel Clement, Aymeric Leray, Alexandre Bouhelier, Eric Finot,Journal : Phys. Chem. Chem. Phys. - n° 19 - 2017 - 458-466
Visualization of cell-cell interactions dynamics in early Xenopus embryos reveals direct interaction between PAPC and XCC at the gastrula stage.
F. B. Riquet, F. Sipieter, A. Leray, C. Spriet, H. Badache, D. Vicogne, L. Heliot, Y. Saka,Journal : Mol. Biol. Cell - n° 27 - 2016 -
Myofibril Changes in the Copepod Pseudodiaptomus marinus Exposed to Haline and Thermal Stresses
Ali Ibrahim, Anissa Souissi, Aymeric Leray, Laurent Heliot, Bernard Vandenbunder, Sami Souissi,Journal : PLoS One - n° 11 - 2016 -
Sorting of Single Biomolecules based on Fourier Polar Representation of Surface Enhanced Raman Spectra
Aymeric Leray, Thibault Brule, Mickael Buret, Gerard Colas des Francs, Alexandre Bouhelier, Alain Dereux, Eric Finot,Journal : Sci Rep - n° 6 - 2016 - 20383
Statistical Performance Analysis of a Fast Super-Resolution Technique Using Noisy Translations
Pierre Chainais, Aymeric Leray,Journal : IEEE Trans. Image Process. - n° 25 - 2016 - 1699-1712
Label-free microscopy and stress responses reveal the functional organization of Pseudodiaptomus marinus copepod myofibrils
Ali Ibrahim, Charles Henri Hage, Anissa Souissi, Aymeric Leray, Laurent Heliot, Sami Souissi, Bernard Vandenbunder,Journal : J. Struct. Biol. - n° 191 - 2015 - 224-235
Unraveling the time cross correlations of an emitter switching between two states with the same fluorescence intensity
F. Eloi, H. Frederich, A. Leray, S. Buil, X. Quelin, B. Ji, E. Giovanelli, N. Lequeux, B. Dubertret, J. -P. Hermier,Journal : Opt. Express - n° 23 - 2015 - 29921-29928
Statistical and Fourier Analysis for In-line Concentration Sensitivity in Single Molecule Dynamic-SERS
Thibault Brule, Alexandre Bouhelier, Helene Yockell-Lelievre, Jean-Emmanuel Clement, Aymeric Leray, Alain Dereux, Eric Finot,Journal : ACS Photonics - n° 2 - 2015 - 1266-1271
Application of a High Power Yb Fiber-Based Laser Compatible With Commercial Optical Parametric Oscillator for Coherent Anti-Stokes Raman Scattering Microscopy
Charles-Henri Hage, Simon Boisset, Ali Ibrahim, Franck Morin, Clemens Hoenninger, Tobias Grunske, Sami Souissi, Laurent Heliot, Aymeric Leray,Journal : Microsc. Res. Tech. - n° 77 - 2014 - 422-430
PRC1 components exhibit different binding kinetics in Polycomb bodies
Bernard Vandenbunder, Nicolas Fourre, Aymeric Leray, Florian Mueller, Pamela Voelkel, Pierre-Olivier Angrand, Laurent Heliot,Journal : Biol. Cell - n° 106 - 2014 - 111-125
Single-molecule controlled emission in planar plasmonic cavities
S. Derom, A. Bouhelier, A. Kumar, A. Leray, J-C. Weeber, S. Buil, X. Quelin, J. P. Hermier, G. Colas des Francs,Journal : Phys. Rev. B - n° 89 - 2014 - 035401
Sorting of Enhanced Reference Raman Spectra of a Single Amino Acid Molecule
Thibault Brule, Helene Yockell-Lelievre, Alexandre Bouhelier, Jeremie Margueritat, Laurent Markey, Aymeric Leray, Alain Dereux, Eric Finot,Journal : J. Phys. Chem. C - n° 118 - 2014 - 17975-17982
Implementation of Transportation Distance for Analyzing FLIM and FRET Experiments
Philippe Heinrich, Mariano Gonzalez Pisfil, Jonas Kahn, Laurent Heliot, Aymeric Leray,Journal : Bull. Math. Biol. - n° 76 - 2014 - 2596-2626
From FRET Imaging to Practical Methodology for Kinase Activity Sensing in Living Cells
Francois Sipieter, Pauline Vandame, Corentin Spriet, Aymeric Leray, Pierre Vincent, Dave Trinel, Jean-Francois Bodart, Franck B. Riquet, Laurent Heliot,Journal : Prog. Molec. Biol. Transl. Sci. - n° 113 - 2013 - 145-216
Measuring the scattering coefficient of turbid media from two-photon microscopy
David Sevrain, Matthieu Dubreuil, Aymeric Leray, Christophe Odin, Yann Le Grand,Journal : Opt. Express - n° 21 - 2013 - 25221-25235
The Elongation Complex Components BRD4 and MLLT3/AF9 Are Transcriptional Coactivators of Nuclear Retinoid Receptors
Sebastien Flajollet, Christophe Rachez, Maheul Ploton, Celine Schulz, Rozenn Gallais, Raphael Metivier, Michal Pawlak, Aymeric Leray, Al Amine Issulahi, Laurent Heliot, Bart Staels, Gilles Salbert, Philippe Lefebvre,Journal : PLoS One - n° 8 - 2013 -
827Spatio-Temporal Quantification of FRET in Living Cells by Fast Time-Domain FLIM: A Comparative Study of Non-Fitting Methods
Aymeric Leray, Sergi Padilla-Parra, Julien Roul, Laurent Heliot, Marc Tramier,Journal : PLoS One - n° 8 - 2013 -
Generalization of the polar representation in time domain fluorescence lifetime imaging microscopy for biological applications: practical implementation
A. Leray, C. Spriet, D. Trinel, Y. Usson, L. Heliot,Journal : J. Microsc. - n° 248 - 2012 - 66-76
Upgrading Time Domain FLIM Using an Adaptive Monte Carlo Data Inflation Algorithm
Dave Trinel, Aymeric Leray, Corentin Spriet, Yves Usson, Laurent Heliot,Journal : Cytom. Part A - n° - 2011 - 528-537
Quantitative Comparison of Polar Approach Versus Fitting Method in Time Domain FLIM Image Analysis
A. Leray, C. Spriet, D. Trinel, R. Blossey, Y. Usson, L. Heliot,Journal : Cytom. Part A - n° - 2011 - 149-158
Control of pulse-to-pulse fluctuations in visible supercontinuum
A. Kudlinski, B. Barviau, A. Leray, C. Spriet, L. Heliot, A. Mussot,Journal : Opt. Express - n° 18 - 2010 - 27445-27454
Three-Dimensional Polar Representation for Multispectral Fluorescence Lifetime Imaging Microscopy
A. Leray, C. Spriet, D. Trinel, Laurent Heliot,Journal : Cytom. Part A - n° - 2009 - 1007-1014
Optimized Protocol of a Frequency Domain Fluorescence Lifetime Imaging Microscope for FRET Measurements
Aymeric Leray, Franck B. Riquet, Elodie Richard, Corentin Spriet, Dave Trinel, Laurent Heliot,Journal : Microsc. Res. Tech. - n° 72 - 2009 - 371-379
Enhanced background rejection in thick tissue with differential-aberration two-photon microscopy
A. Leray, K. Lillis, J. Mertz,Journal : Biophys. J. - n° 94 - 2008 - 1449-1458
Non-descanned versus descanned epifluorescence collection in two-photon microscopy: Experiments and Monte Carlo simulations
Y. Le Grand, A. Leray, T. Guilbert, C. Odin,Journal : Opt. Commun. - n° 281 - 2008 - 5480-5486
Out-of-focus fluorescence collection in two-photon microscopy of scattering media
A. Leray, C. Odin, Y. Le Grand,Journal : Opt. Commun. - n° 281 - 2008 - 6139-6144
Spatially distributed two-photon excitation fluorescence in scattering media: Experiments and time-resolved Monte Carlo simulations
A. Leray, C. Odin, E. Huguet, F. Amblard, Y. Le Grand,Journal : Opt. Commun. - n° 272 - 2007 - 269-278
Rejection of two-photon fluorescence background in thick tissue by differential aberration imaging
Aymeric Leray, Jerome Mertz,Journal : Opt. Express - n° 14 - 2006 - 10565-10573
Effect of the orientational disorder on the hyperpolarizability measurement of amphiphilic push-pull chromophores in Langmuir-Blodgett monolayers
A Leray, D Rouede, C Odin, Y Le Grand, O Mongin, M Blanchard-Desce,Journal : Opt. Commun. - n° 247 - 2005 - 213-223
Organization and orientation of amphiphilic push-pull chromophores deposited in Langmuir-Blodgett monolayers studied by second harmonic generation and atomic force microscopy
A Leray, L Leroy, Y Le Grand, C Odin, A Renault, V Vie, D Rouede, T Mallegol, O Mongin, MHV Werts, M Blanchard-Desce,Journal : Langmuir - n° 20 - 2004 - 8165-8171
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