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Fiche de : Aymeric LERAY

Département :
Nanosciences


Fonction :

Chargé de Recherche CNRS



Localisation :

UFR Sciences et Techniques, Batiment Mirande (Dijon), Aile D, Bureau DR11A

Tél. : +33 (0)3 80 39 59 04
E-mail : aymeric.leray@u-bourgogne.fr

Dr. Aymeric Leray (1979), chercheur CNRS, a obtenu sa thèse en Physique en 2005 à l’université de Rennes (France). Après un premier post-doc avec Jerome Mertz à Boston University (USA) et un second avec Laurent Héliot à l’Institut de Recherche Interdisciplinaire (IRI) à Lille, il est recruté en 2010 en tant que chercheur CNRS dans le groupe Biophotonique à l’IRI à Lille. Depuis 2014, il travaille à l'ICB. Ses travaux de recherche gravitent principalement autour de la microscopie optique non linéaire appliquée à la Biologie et de la détection de molécules uniques pour les biocapteurs.

  • – ANR SpecTra (Etude spectroscopique de nanoparticules piégées optiquement), 2016-2020
  •  
  • – Equipex ImaginEx BioMed (Imagerie innovante d’excellence dans le domaine biomédical: plateforme de criblage à haut-débit et à très haut-contenu), 2011-2021

A readily usable two-photon fluorescence lifetime microendoscope

Charles-Henri Hage, Pierre Leclerc, Marc Fabert, Sylvia M. Bardet, Julien Brevier, Guillaume Ducourthial, Tigran Mansuryan, Aymeric Leray, Alexandre Kudlinski, Frederic Louradour,
Journal : J. Biophotonics - n° 12 - 2019 -

Conformational Changes and Charge Transfer in Biomolecules Resolved Using Dynamic Enhanced Raman Correlation Spectroscopy

Aymeric Leray, Jean-Emmanuel Clement, Alexandre Bouhelier, Eric Finot,
Journal : J. Phys. Chem. B - n° 123 - 2019 - 1931-1938

Spectral pointillism of enhanced Raman scattering for accessing structural and conformational information on single protein

Jean-Emmanuel Clement, Aymeric Leray, Alexandre Bouhelier, Eric Finot,
Journal : Phys. Chem. Chem. Phys. - n° 19 - 2017 - 458-466

Visualization of cell-cell interactions dynamics in early Xenopus embryos reveals direct interaction between PAPC and XCC at the gastrula stage.

F. B. Riquet, F. Sipieter, A. Leray, C. Spriet, H. Badache, D. Vicogne, L. Heliot, Y. Saka,
Journal : Mol. Biol. Cell - n° 27 - 2016 -

Myofibril Changes in the Copepod Pseudodiaptomus marinus Exposed to Haline and Thermal Stresses

Ali Ibrahim, Anissa Souissi, Aymeric Leray, Laurent Heliot, Bernard Vandenbunder, Sami Souissi,
Journal : PLoS One - n° 11 - 2016 -

Sorting of Single Biomolecules based on Fourier Polar Representation of Surface Enhanced Raman Spectra

Aymeric Leray, Thibault Brule, Mickael Buret, Gerard Colas des Francs, Alexandre Bouhelier, Alain Dereux, Eric Finot,
Journal : Sci Rep - n° 6 - 2016 - 20383

Statistical Performance Analysis of a Fast Super-Resolution Technique Using Noisy Translations

Pierre Chainais, Aymeric Leray,
Journal : IEEE Trans. Image Process. - n° 25 - 2016 - 1699-1712

Label-free microscopy and stress responses reveal the functional organization of Pseudodiaptomus marinus copepod myofibrils

Ali Ibrahim, Charles Henri Hage, Anissa Souissi, Aymeric Leray, Laurent Heliot, Sami Souissi, Bernard Vandenbunder,
Journal : J. Struct. Biol. - n° 191 - 2015 - 224-235

Unraveling the time cross correlations of an emitter switching between two states with the same fluorescence intensity

F. Eloi, H. Frederich, A. Leray, S. Buil, X. Quelin, B. Ji, E. Giovanelli, N. Lequeux, B. Dubertret, J. -P. Hermier,
Journal : Opt. Express - n° 23 - 2015 - 29921-29928

Statistical and Fourier Analysis for In-line Concentration Sensitivity in Single Molecule Dynamic-SERS

Thibault Brule, Alexandre Bouhelier, Helene Yockell-Lelievre, Jean-Emmanuel Clement, Aymeric Leray, Alain Dereux, Eric Finot,
Journal : ACS Photonics - n° 2 - 2015 - 1266-1271

Application of a High Power Yb Fiber-Based Laser Compatible With Commercial Optical Parametric Oscillator for Coherent Anti-Stokes Raman Scattering Microscopy

Charles-Henri Hage, Simon Boisset, Ali Ibrahim, Franck Morin, Clemens Hoenninger, Tobias Grunske, Sami Souissi, Laurent Heliot, Aymeric Leray,
Journal : Microsc. Res. Tech. - n° 77 - 2014 - 422-430

PRC1 components exhibit different binding kinetics in Polycomb bodies

Bernard Vandenbunder, Nicolas Fourre, Aymeric Leray, Florian Mueller, Pamela Voelkel, Pierre-Olivier Angrand, Laurent Heliot,
Journal : Biol. Cell - n° 106 - 2014 - 111-125

Single-molecule controlled emission in planar plasmonic cavities

S. Derom, A. Bouhelier, A. Kumar, A. Leray, J-C. Weeber, S. Buil, X. Quelin, J. P. Hermier, G. Colas des Francs,
Journal : Phys. Rev. B - n° 89 - 2014 - 035401

Sorting of Enhanced Reference Raman Spectra of a Single Amino Acid Molecule

Thibault Brule, Helene Yockell-Lelievre, Alexandre Bouhelier, Jeremie Margueritat, Laurent Markey, Aymeric Leray, Alain Dereux, Eric Finot,
Journal : J. Phys. Chem. C - n° 118 - 2014 - 17975-17982

Implementation of Transportation Distance for Analyzing FLIM and FRET Experiments

Philippe Heinrich, Mariano Gonzalez Pisfil, Jonas Kahn, Laurent Heliot, Aymeric Leray,
Journal : Bull. Math. Biol. - n° 76 - 2014 - 2596-2626

From FRET Imaging to Practical Methodology for Kinase Activity Sensing in Living Cells

Francois Sipieter, Pauline Vandame, Corentin Spriet, Aymeric Leray, Pierre Vincent, Dave Trinel, Jean-Francois Bodart, Franck B. Riquet, Laurent Heliot,
Journal : Prog. Molec. Biol. Transl. Sci. - n° 113 - 2013 - 145-216

Measuring the scattering coefficient of turbid media from two-photon microscopy

David Sevrain, Matthieu Dubreuil, Aymeric Leray, Christophe Odin, Yann Le Grand,
Journal : Opt. Express - n° 21 - 2013 - 25221-25235

The Elongation Complex Components BRD4 and MLLT3/AF9 Are Transcriptional Coactivators of Nuclear Retinoid Receptors

Sebastien Flajollet, Christophe Rachez, Maheul Ploton, Celine Schulz, Rozenn Gallais, Raphael Metivier, Michal Pawlak, Aymeric Leray, Al Amine Issulahi, Laurent Heliot, Bart Staels, Gilles Salbert, Philippe Lefebvre,
Journal : PLoS One - n° 8 - 2013 -

827Spatio-Temporal Quantification of FRET in Living Cells by Fast Time-Domain FLIM: A Comparative Study of Non-Fitting Methods

Aymeric Leray, Sergi Padilla-Parra, Julien Roul, Laurent Heliot, Marc Tramier,
Journal : PLoS One - n° 8 - 2013 -

Generalization of the polar representation in time domain fluorescence lifetime imaging microscopy for biological applications: practical implementation

A. Leray, C. Spriet, D. Trinel, Y. Usson, L. Heliot,
Journal : J. Microsc.. - n° 248 - 2012 - 66-76

Upgrading Time Domain FLIM Using an Adaptive Monte Carlo Data Inflation Algorithm

Dave Trinel, Aymeric Leray, Corentin Spriet, Yves Usson, Laurent Heliot,
Journal : Cytom. Part A - n° - 2011 - 528-537

Quantitative Comparison of Polar Approach Versus Fitting Method in Time Domain FLIM Image Analysis

A. Leray, C. Spriet, D. Trinel, R. Blossey, Y. Usson, L. Heliot,
Journal : Cytom. Part A - n° - 2011 - 149-158

Control of pulse-to-pulse fluctuations in visible supercontinuum

A. Kudlinski, B. Barviau, A. Leray, C. Spriet, L. Heliot, A. Mussot,
Journal : Opt. Express - n° 18 - 2010 - 27445-27454

Three-Dimensional Polar Representation for Multispectral Fluorescence Lifetime Imaging Microscopy

A. Leray, C. Spriet, D. Trinel, Laurent Heliot,
Journal : Cytom. Part A - n° - 2009 - 1007-1014

Optimized Protocol of a Frequency Domain Fluorescence Lifetime Imaging Microscope for FRET Measurements

Aymeric Leray, Franck B. Riquet, Elodie Richard, Corentin Spriet, Dave Trinel, Laurent Heliot,
Journal : Microsc. Res. Tech. - n° 72 - 2009 - 371-379

Enhanced background rejection in thick tissue with differential-aberration two-photon microscopy

A. Leray, K. Lillis, J. Mertz,
Journal : Biophys. J. - n° 94 - 2008 - 1449-1458

Non-descanned versus descanned epifluorescence collection in two-photon microscopy: Experiments and Monte Carlo simulations

Y. Le Grand, A. Leray, T. Guilbert, C. Odin,
Journal : Opt. Commun. - n° 281 - 2008 - 5480-5486

Out-of-focus fluorescence collection in two-photon microscopy of scattering media

A. Leray, C. Odin, Y. Le Grand,
Journal : Opt. Commun. - n° 281 - 2008 - 6139-6144

Spatially distributed two-photon excitation fluorescence in scattering media: Experiments and time-resolved Monte Carlo simulations

A. Leray, C. Odin, E. Huguet, F. Amblard, Y. Le Grand,
Journal : Opt. Commun. - n° 272 - 2007 - 269-278

Rejection of two-photon fluorescence background in thick tissue by differential aberration imaging

Aymeric Leray, Jerome Mertz,
Journal : Opt. Express - n° 14 - 2006 - 10565-10573

Effect of the orientational disorder on the hyperpolarizability measurement of amphiphilic push-pull chromophores in Langmuir-Blodgett monolayers

A Leray, D Rouede, C Odin, Y Le Grand, O Mongin, M Blanchard-Desce,
Journal : Opt. Commun. - n° 247 - 2005 - 213-223

Organization and orientation of amphiphilic push-pull chromophores deposited in Langmuir-Blodgett monolayers studied by second harmonic generation and atomic force microscopy

A Leray, L Leroy, Y Le Grand, C Odin, A Renault, V Vie, D Rouede, T Mallegol, O Mongin, MHV Werts, M Blanchard-Desce,
Journal : Langmuir - n° 20 - 2004 - 8165-8171
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